Zdravo,

Ja, blogi o domačih kremah za sončenje tudi meni malo dvignejo pritisk. Ker ponavadi temeljijo na predpostavki “naravno = varno” in “sintetično, nenaravno = nevarno”. Pa svet žal ni tako črno-bel 🙂 V svoji začetni navdušenosti sem tudi sama doma izdelala kremo za sončenje (še celo na UV svetlobi sem jo “testirala”), pa sem s tem početjem kljub vsemu nehala, ko sem se v tematiko bolj poglobila.
Se pa tudi jaz veselim novih raziskav s področja UV zaščite! 🙂

Zdravo,
tale zgornji komentar sem napisala že kar nekaj časa nazaj, ko sem pred tem prispevkom naletela na kar nekaj blogov o izdelovanju domačih sončnih krem, ki so me kar malo razjezile. Svojo jezo sem definitivno zlila na neprimeren način in na neprimeren prispevek. Zato se iskreno opravičujem. Hvala za napisano literaturo, UV filtri so sigurno sestavine, na katerih bo potrebno narediti še veliko študij, da bomo vedeli kaj in kako…

Absolutno se strinjam, da je potrebno navajati vire informacij. Tale zapis je bil mišljen kot en hiter pregled problematike, saj bi se o vsakem podnaslovu dalo napisati razširjen prispevek s pripadajočimi referencami.
Tule so torej znanstveni članki, iz katerih so bili črpani podatki o kemičnih filtrih, navedene so tudi reference, ki se tičejo problematike kontaktnega dermatitisa in draženja kože – še en problem organskih UV filtrov, o katerem še nisem spregovorila. Če do kakšnega izmed njih na Fakulteti za farmacijo ni dostopa, se lahko potrudim, da vam pošljem pdf.
Bi pa v prihodnje prosila za malo bolj kulturen nivo izražanja.

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Heneweer M, Muusse M, van den Berg M, Sanderson JT. 2005. Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells. Toxicology and Applied Pharmacology 208(2): 170-177.

Kunz PY, Galicia HF, Fent K. 2006. Comparison of in vitro and in vivo estrogenic activity of UV filters in fish. Toxicol Sci 90(2): 349-361.

Nakagawa Y, Suzuki T. 2002. Metabolism of 2-hydroxy-4-methoxybenzophenone in isolated rat hepatocytes and xenoestrogenic effects of its metabolites on MCF-7 human breast cancer cells. Chem Biol Interact 139(2): 115-128.

Sarveiya V, Risk S, Benson HAE. 2004. Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 803(2): 225-231.

Rodriguez E, Valbuena MC, Rey M, Porras de Quintana L. 2006. Causal agents of photoallergic contact dermatitis diagnosed in the National Institute of Dermatology of Colombia. Photodermatol Photoimmunol Photomed 22(4): 189-92.

Klinubol P, Asawanonda P, Wanichwecharungruang SP. 2008. Transdermal penetration of UV filters. Skin Pharmacol Physiol. 21(1): 23-9.

SCCNFP (Scientific Committee on Cosmetic Products and Non-Food Products Intended for Consumers). 2006. Opinion concerning Homosalate.

Walters KA, Brain KR, Howes D, James VJ, Kraus AL, Teetsel NM, Toulon M, Watkinson AC, Gettings SD. 1997. Percutaneous penetration of octyl salicylate from representative sunscreen formulations through human skin in vitro. Food Chem Toxicol 35(12): 1219-25.

Shaw, DW. 2006. Allergic contact dermatitis from octisalate and cis-3-hexenyl salicylate. Dermatitis 17(3): 152-5.

Singh M, Beck MH. 2007. Octyl salicylate: a new contact sensitivity. Contact Dermatitis 56(1): 48.

Hayden CGJ, Cross SE, Anderson C, Saunders NA, Roberts MS. 2005. Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin Pharmacology and Physiology 18(4): 170-174.

Bryden AM, Moseley H, Ibbotson SH, Chowdhury MMU, et al. 2006. Photopatch testing of 1155 patients: results of the U.K. multicentre photopatch study group. British Journal of Dermatology, 155: 737–747.